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KMID : 1013220140120010031
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Jouranl of the Korean Society of Clinical Toxicology
2014 Volume.12 No. 1 p.31 ~ p.34
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A Case of Acute Hepatic Failure due to Acetaminophen Overdose Treated with Molecular Adsorbents Recirculating System®
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Yang Byung-Keun
You Je-Sung
Joo Young-Seon
Chung Sung-Phil
Lee Hahn-Shick
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Abstract
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We report on a patient who developed acute hepatic failure despite intravenous N-acetyl cysteine therapy who was treated with the Molecular Adsorbents Recirculating System (MARS). She presented 20 hours after the ingestion of 13 g of acetaminophen. The MARS is based on albumin dialysis principle which can be applied for patients with acute poisoning from drugs that have high protein-binding capacity because of its ability to selectively remove from circulation protein-bound toxins. The clinical toxicologist should be consider this technology when treating patients with hepatic failure following acetaminophen poisoning.
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KEYWORD
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Poisoning, Acetaminophen, Liver failure
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